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nonlinear regression for a sigmoidal concentration response curve graphpad prism v. 4.0  (GraphPad Software Inc)


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    GraphPad Software Inc nonlinear regression for a sigmoidal concentration response curve graphpad prism v. 4.0
    Nonlinear Regression For A Sigmoidal Concentration Response Curve Graphpad Prism V. 4.0, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sigmoidal+nonlinear+regression+graphpad+prism+4%2E0/nonlinear+regression+for+a+sigmoidal+concentration+response+curve+graphpad+prism+v++4+0/pmc04399838-62-11-15
    Average 90 stars, based on 1 article reviews
    nonlinear regression for a sigmoidal concentration response curve graphpad prism v. 4.0 - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Functional Assay:

    Article Title: Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B 2 receptor antagonism in human synovial fibroblasts
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration-response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Bradykinin and B 2 receptor antagonism in rat and human articular chondrocytes
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration–response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Comparative antagonist pharmacology at the native mouse bradykinin B 2 receptor: radioligand binding and smooth muscle contractility studies
    Article Snippet: .. Functional data (concentration–response curves) were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing the 50% (EC 50 ) of the maximal response ( E max ). ..

    Article Title: MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.
    Article Snippet: The pharmacological characterization of the novel nonpeptide antagonist for the B2 receptor, namely MEN16132 (4-(S)-Amino-5-(4-{4-[2,4dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl}piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride) is presented.. The affinity of MEN16132 for the bradykinin B2 receptor has been investigated by means of competition studies at [ H]bradykinin binding to membranes prepared from Chinese Hamster Ovary (CHO) cells expressing the human bradykinin B2 receptor (pKi 10.5), human lung fibroblasts (pKi 10.5), guinea pig airways (pKi 10.0), guinea pig ileum longitudinal smooth muscle (pKi 10.2), or guinea pig cultured colonic myocytes (pKi 10.3).. In all assays MEN16132 was as potent as the peptide antagonist Icatibant, and from 3to 100-fold more potent than the reference nonpeptide antagonists FR173657 or LF16-0687.

    Concentration Assay:

    Article Title: Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B 2 receptor antagonism in human synovial fibroblasts
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration-response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Bradykinin and B 2 receptor antagonism in rat and human articular chondrocytes
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration–response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Comparative antagonist pharmacology at the native mouse bradykinin B 2 receptor: radioligand binding and smooth muscle contractility studies
    Article Snippet: .. Functional data (concentration–response curves) were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing the 50% (EC 50 ) of the maximal response ( E max ). ..

    Article Title: MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.
    Article Snippet: The pharmacological characterization of the novel nonpeptide antagonist for the B2 receptor, namely MEN16132 (4-(S)-Amino-5-(4-{4-[2,4dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl}piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride) is presented.. The affinity of MEN16132 for the bradykinin B2 receptor has been investigated by means of competition studies at [ H]bradykinin binding to membranes prepared from Chinese Hamster Ovary (CHO) cells expressing the human bradykinin B2 receptor (pKi 10.5), human lung fibroblasts (pKi 10.5), guinea pig airways (pKi 10.0), guinea pig ileum longitudinal smooth muscle (pKi 10.2), or guinea pig cultured colonic myocytes (pKi 10.3).. In all assays MEN16132 was as potent as the peptide antagonist Icatibant, and from 3to 100-fold more potent than the reference nonpeptide antagonists FR173657 or LF16-0687.

    Inhibition:

    Article Title: Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B 2 receptor antagonism in human synovial fibroblasts
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration-response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Bradykinin and B 2 receptor antagonism in rat and human articular chondrocytes
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration–response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Control:

    Article Title: Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B 2 receptor antagonism in human synovial fibroblasts
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration-response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..

    Article Title: Bradykinin and B 2 receptor antagonism in rat and human articular chondrocytes
    Article Snippet: .. Functional data were fitted by sigmoidal nonlinear regression (GraphPad Prism 4.0) to determine the agonist concentration producing 50% (EC 50 ) of the maximal response (E max ) from the concentration–response curves, and the antagonist concentration producing 50% inhibition (IC 50 ) of the control agonist response. ..



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